Scientific Director

1962: Degree in Medicine and Surgery at the University of Bologna, with honors.

1965: Specialization in Urology at the University of Bologna.

• 1963-1971: Assistant in Biology, Institute of Histology, Faculty of Medicine and Surgery – University of Bologna.
• 1968 – 1971: Lecturer in Histology, Faculty of Medicine and Surgery – University of Chieti.
• 1968 -1977: Lecturer in Biology, Faculty of Medicine and Surgery – University of Bologna.
• 1971- 1977: Full Professor of Histology, Faculty of Medicine and Surgery – University of Chieti.
• 1972-1980: Dean of the Faculty of Medicine and Surgery – University of Chieti.
• 1982-1989: President of the “Rizzoli Orthopaedic Institutes”, Bologna.
• 1989 – 1993: General Director, National Institute of Health, Rome.
• From 1977: Full Professor of Normal Human Anatomy, Faculty of Medicine and Surgery, University of Bologna.
• From January 1st, 2008 he is Scientific Director of the Rizzoli Orthopedic Institute.

Member of the “National Council of Research”.
Member of the “National Council of Science and Technique”.
Member of several commissions of public health, as General Director of the National Institute of Health.
President of the Italian Society of Histochemistry (1982-1985).
Member of the FIRB Commission of the Ministry of Education, University and Research (MIUR).

Member of the “Science Academy” of the University of Bologna.
“Order of Minerva”, gold medal by the University of Chieti.
Gold medal for Public Health from the Italian Government.
Honorary Degree in Medicine - Jefferson University Medical School - Philadelphia, PA USA.
Scanno Prize for Medicine.
Prize “Bruno da Longobucco”(University of Padua).

Guest lecturer at several International Conventions, among which:

• Symposium on Regulation of Enzyme Activity and Synthesis in Normal and Neoplastic tissues, Indiana University, USA (from 1977 to 2002);
• Symposium on Support Therapy for hemopathies, Pescara, Italy, 1976;
• Annual Meeting of the American Oil Chemistry Society, Chicago, USA, 1983;
• Tenth Italian Congress on Fatty Substances, 1970;
• Congress of the Italian Society of Anatomy, 1974;
• International School of Applied Cellular Biology, E. Maiorana Centre, Erice, Italia, 1973;
• International Course on the Biology of the Lymphocyte, E. Maiorana Centre, Erice, Italia, 1974;
• Congress of the Federation of European Biochemical Societies “FEBS”, Helsinki, Finlandia, 1994.

Member of the Editorial Board of the dell'European Journal of Histochemistry and of the Bulletin of Molecular Biology and Medicine.
He is referee for Biochem Biophys. Res Comm., Biochim. Biophys. Acta, Immunology Lett., Phys. Chem. Lipids.

In 2006, the review BBA Mol. Cell Biol. Lipids (among the “top-ten” reviews in Biology and Biochemistry, according to the ISI Science Watch) dedicated to Prof. Manzoli the Special Issue “Lipid Signaling in the nucleus”, of which he is also Honorary Editor.
He is author of 170 print publications on international and national reviews with audit committee. Total Impact Factor (ISI –JCR 2005) 403; quotes in the last 10 years (ISI-JCR 2005) 1427.

The main topics of his scientific activities regard:

• The structure of biological membranes, especially of cellular, nuclear, mitochondrial membranes, membrane of the ergastoplasmic reticulum, of the Golgi apparatus, of the synaptic small blisters and of myelin sheath;
• Interaction between macro and micro molecules, in particular between the DNA and histones with phospholipids;
• The structure of Chromatin;
• Analysis of nuclear signals;
• Structure and functions of lymphocytes B and T.